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Verified clinical guidelines and emergency management protocols.
| Term | Definition | Clinical Significance |
|
PPH (Traditional - Vaginal)
|
Blood loss ≥500 mL after vaginal delivery | Threshold for documentation; often underestimates true loss |
|
PPH (Traditional - CS)
|
Blood loss ≥1000 mL after caesarean section | Higher baseline expected loss in CS |
|
Severe PPH
|
Blood loss ≥1000 mL regardless of mode | Requires aggressive intervention |
|
Clinical PPH (Preferred)
|
Blood loss causing haemodynamic instability OR requiring intervention | Most practical definition; treat the patient, not the number |
|
Primary PPH
|
Within 24 hours of delivery | Most common, most dangerous |
|
Secondary PPH
|
24 hours to 12 weeks postpartum | Usually infection or retained products |
🚨 Clinical Pearl: Visual estimation underestimates blood loss by 30-50%. A soaked maternity pad holds ~100 mL; a soaked under-buttock drape holds ~500-1000 mL. When in doubt, treat as PPH.
| Parameter | Data |
| Incidence | 2-4% of all deliveries; up to 6% in some settings |
| Maternal mortality contribution | 38% of direct maternal deaths (leading cause) |
| Case fatality rate | 1% (higher in rural/resource-limited settings) |
| Time to death | Can occur within 2 hours if untreated |
| Risk Factors | Mechanism |
|
Overdistended uterus
|
Multiple pregnancy, polyhydramnios, macrosomia (>4 kg) |
|
Uterine muscle fatigue
|
Prolonged labour, rapid labour (precipitate), prolonged oxytocin use |
|
Uterine muscle impairment
|
Grand multiparity (≥5), previous PPH, fibroids, chorioamnionitis |
|
Drug-induced relaxation
|
MgSO₄, tocolytics (terbutaline, nifedipine), halogenated anaesthetics |
|
Other
|
Full bladder (prevents contraction), uterine inversion |
| Type | Causes | Clinical Features |
|
Perineal tears
|
Precipitate delivery, large baby, instrumental delivery | Visible bleeding from perineum |
|
Vaginal tears
|
Instrumental delivery, malpresentation | Bleeding with contracted uterus |
|
Cervical tears
|
Rapid dilatation, pushing before full dilatation | Bleeding despite contracted uterus; need speculum exam |
|
Uterine rupture
|
Previous CS, obstructed labour, oxytocin excess | Sudden pain, shock, loss of contractions |
|
Uterine inversion
|
Cord traction before separation, fundal pressure | Mass at/outside introitus, shock out of proportion |
|
Broad ligament haematoma
|
Extension of uterine incision (CS), instrumental | Expanding pelvic mass, shock |
| Type | Causes | Clinical Features |
|
Retained placenta
|
Placenta accreta spectrum, manual removal failure | Placenta not delivered within 30 min |
|
Retained cotyledon/membrane
|
Incomplete placental examination | Uterus doesn’t contract fully; check placenta |
|
Retained blood clots
|
Atony, coagulopathy | Soft uterus despite uterotonics; clots on massage |
|
Succenturiate lobe
|
Abnormal placentation | Vessels running to edge of membranes |
| Type | Causes | Clinical Features |
|
Pre-existing
|
Von Willebrand disease, haemophilia carriers, ITP, anticoagulant use | Known history; bleeding from multiple sites |
|
Acquired - Pregnancy
|
Severe preeclampsia/HELLP, placental abruption, amniotic fluid embolism, IUFD (especially >4 weeks) | Oozing from IV sites, wound, no clot formation |
|
Acquired - Dilutional
|
Massive crystalloid resuscitation, massive transfusion without FFP | After large volume replacement |
|
DIC
|
Abruption, sepsis, AFE, IUFD | Consumptive; low fibrinogen, prolonged PT/aPTT |
| Risk Level | Factors | Action |
|
HIGH RISK
|
Previous PPH, placenta praevia, suspected accreta, multiple pregnancy, polyhydramnios, large fibroids, bleeding disorder, severe anaemia (Hb <7), anticoagulant use | Deliver at CEmONC facility with blood bank; Group & Save/Crossmatch; senior obstetrician; anaesthesia standby |
|
MODERATE RISK
|
Grand multiparity (≥5), previous CS, overdistended uterus, Hb 7-9, obesity | Deliver at facility with blood transfusion capability; Group & Save; IV access before delivery |
|
LOW RISK
|
No risk factors identified | Routine AMTSL; be prepared (PPH can occur without risk factors) |
⚠️ 40% of PPH occurs in women with NO identifiable risk factors. Always be prepared.
| New Risk Factor | Action |
| Prolonged first stage (>12h nullipara, >10h multipara) | Prepare blood, senior involvement |
| Prolonged second stage | Consider instrumental vs CS; have uterotonics ready |
| Chorioamnionitis | IV antibiotics; anticipate atony |
| Instrumental delivery | Check for trauma; have sutures ready |
| Emergency CS | Anticipate higher blood loss |
| MgSO₄ use | Atony risk increased |
| Component | Technique | Timing |
|
1. Prophylactic Uterotonic
|
Oxytocin 10 IU IM (preferred) OR IV over 1-2 min | Within 1 minute of delivery of baby |
|
2. Controlled Cord Traction (CCT)
|
Apply steady traction on cord while providing counter-traction above pubic symphysis | Only when uterus contracted and cord lengthening |
|
3. Uterine Massage
|
Gentle fundal massage after placental delivery | Until uterus well-contracted |
| Drug | Dose | Route | Notes |
|
Oxytocin
|
10 IU | IM (preferred) or slow IV | First choice; safest profile |
|
Carbetocin
|
100 mcg | Single IM/IV dose | Longer acting; useful where cold chain limited |
|
Oxytocin + Ergometrine (Syntometrine)
|
5 IU + 0.5 mg | IM | More effective but more side effects; avoid in HTN |
|
Misoprostol
|
600 mcg | Oral | Where oxytocin unavailable; more side effects |
| Recommendation | Details |
| Timing | Clamp cord 1-3 minutes after delivery (if baby vigorous) |
| Benefit | Increased neonatal haemoglobin, iron stores |
| Exception | If mother bleeding heavily OR baby needs resuscitation → clamp immediately |
| Sign | What to Look For |
|
Visible bleeding
|
Continuous trickle, gush, soaking drapes, pooling |
|
Uterine fundus
|
Soft, boggy, above umbilicus (atony) vs firm (trauma/tissue) |
|
Vital signs
|
Tachycardia, hypotension, tachypnoea |
|
Patient symptoms
|
Weakness, dizziness, thirst, confusion, restlessness |
|
Appearance
|
Pallor, cold/clammy, air hunger |
| SI Value | Interpretation | Estimated Blood Loss | Required Action |
| 0.7-0.9 | Normal | <500 mL | Monitor, continue routine care |
| 0.9-1.1 | Mild shock | 500-1000 mL | Alert team, prepare interventions |
| 1.1-1.5 | Moderate shock | 1000-1500 mL |
Aggressive intervention
|
| >1.5 | Severe shock | >1500 mL |
Massive transfusion protocol
|
🚨 Why Shock Index Matters: Pregnant women maintain BP until 30-40% blood volume lost due to physiological hypervolaemia. By the time BP drops, patient is in severe shock. Tachycardia and rising SI are earlier warning signs.
| Method | Technique |
|
Weighing
|
Weigh blood-soaked items; 1 g = 1 mL blood (subtract dry weight) |
|
Graduated drapes
|
Calibrated under-buttock drapes |
|
Estimation aids
|
Visual guides showing soaked swabs, drapes, etc. |
| Item | Approximate Blood Volume |
| Fully soaked maternity pad | 100 mL |
| Fully soaked incontinence pad (large) | 250 mL |
| Blood clot (fist-sized) | 500 mL |
| Fully soaked under-buttock drape | 500-1000 mL |
| Kidney dish (full) | 500 mL |
| Category | Items |
|
Uterotonics
|
Oxytocin 10 IU × 10, Misoprostol 200 mcg × 10, Methylergometrine 0.2 mg × 5, Carboprost 250 mcg × 4 (refrigerated) |
|
Tranexamic acid
|
1 g ampules × 4 |
|
IV supplies
|
16G & 18G cannulas × 4 each, IV sets × 4, 3-way stopcock × 2 |
|
Fluids
|
NS 1L × 4, RL 1L × 4 |
|
Blood administration
|
Blood giving sets × 4, blood warmer if available |
|
UBT
|
Bakri balloon OR Condom catheter kit (Foley 22-24F, condom, silk tie) |
|
Instruments
|
Sponge holding forceps × 2, ovum forceps, Sims speculum, suture material |
|
Drugs
|
Calcium gluconate 10% × 2, Adrenaline 1:1000 × 2, Atropine × 2 |
|
Monitoring
|
BP cuff, pulse oximeter, thermometer |
|
Documentation
|
PPH checklist, observation chart, timer |
| Action | Details |
| Position | Flat with legs elevated OR left lateral if still in labour |
| Airway | Ensure patent; suction if vomiting |
| Oxygen | 8-10 L/min via face mask with reservoir (target SpO₂ ≥95%) |
| Action | Details |
|
IV Access
|
2 large-bore cannulas (16G or 18G) – antecubital fossa preferred |
| If difficult: external jugular, femoral, or intraosseous (EZ-IO) | |
|
Bloods
|
CBC, Group & crossmatch, PT/aPTT/fibrinogen, RFT, LFT |
| ABG with lactate if available | |
|
Crystalloid
|
1-2 L NS or RL rapid bolus (use pressure bag/hand squeeze) |
|
Warming
|
Warm fluids if possible; warm blankets |
|
Catheterize
|
Insert Foley; empty bladder (helps uterine contraction); monitor output |
| Phase | Volume | Endpoint |
|
Initial bolus
|
1-2 L crystalloid over 10-15 min | Assess response |
|
Ongoing
|
Titrate to response | SBP >90, MAP ≥65, UO ≥0.5 mL/kg/hr |
|
Caution
|
Avoid >2L crystalloid without blood | Dilutional coagulopathy, pulmonary oedema |
⚠️ Crystalloid replaces volume, not oxygen-carrying capacity. In ongoing haemorrhage, early blood is critical.
| Drug | Dose & Route | Onset | Notes |
|
Oxytocin (First line)
|
10 IU IM OR slow IV (over 1-2 min) | 2-3 min (IM), immediate (IV) | Maximum bolus 10 IU |
|
Oxytocin infusion
|
20-40 IU in 500 mL NS at 125-250 mL/hr | Continuous | Titrate to uterine tone; max ~60 IU total |
|
Misoprostol
|
800 mcg sublingual (fastest) OR 1000 mcg rectal | 10-15 min | Use if oxytocin unavailable or as add-on; SE: fever, shivering |
|
Methylergometrine
|
0.2 mg IM (preferred) or slow IV | 2-5 min | ❌ Contraindicated: HTN, preeclampsia, cardiac disease |
|
Carboprost (PGF2α)
|
250 mcg deep IM q15-20 min (max 8 doses = 2 mg) | 5-15 min | ❌ Contraindicated: asthma, pulmonary/cardiac/renal disease; store refrigerated |
|
Carbetocin
|
100 mcg single IV/IM dose | Similar to oxytocin | Longer acting; may use instead of oxytocin infusion |
🚨 Do NOT delay escalation. Time is critical. All uterotonics can be given together if needed.
| Parameter | Details |
|
Dose
|
1 g (10 mL of 100 mg/mL solution) IV over 10 minutes |
|
Timing
|
As soon as PPH diagnosed – within 3 hours of birth
|
|
Repeat
|
Second 1 g IV if bleeding continues after 30 minutes OR if bleeding restarts within 24 hours |
|
Evidence
|
WOMAN Trial: 20-30% reduction in death from bleeding if given within 3 hours |
|
Mechanism
|
Inhibits plasmin → reduces fibrin breakdown → stabilizes clot |
🚨 TXA efficacy decreases 10% for every 15 minutes of delay. NO BENEFIT after 3 hours. Give EARLY.
| Injury | Management |
|
Perineal tear (1st-2nd degree)
|
Suture in layers; vaginal mucosa → perineal muscle → skin |
|
Perineal tear (3rd-4th degree)
|
OT, experienced surgeon, proper identification of anal sphincter, layered repair, antibiotics, laxatives postop |
|
Vaginal tear
|
Suture from apex to avoid retraction and haematoma; continuous or interrupted |
|
Cervical tear
|
Start suture above apex of tear; continuous locking or interrupted; may need traction with sponge forceps |
|
Broad ligament haematoma
|
Laparotomy if expanding; evacuate, identify bleeding vessel, ligate; may need internal iliac ligation |
|
Uterine rupture
|
See Section 7 of main document |
|
Uterine inversion
|
See Section 8 of main document |
⚠️ Always inspect placenta and genital tract even if uterus well-contracted – trauma can coexist with atony
| Situation | Management |
| Placenta not delivered, no haemorrhage | Ensure bladder empty; controlled cord traction; wait up to 30-60 min |
| Placenta not delivered, haemorrhage present |
Manual removal under anaesthesia
|
| Trapped placenta (cervix closing) | May need uterine relaxation (terbutaline, nitroglycerin, GA) |
| Morbidly adherent (accreta spectrum) | Senior surgeon, interventional radiology if available, prepare for hysterectomy |
| Situation | Management |
| Retained cotyledon/membranes | Explore uterine cavity under anaesthesia; gentle curettage with large blunt curette (avoid perforation) |
| Retained blood clots preventing contraction | Bimanual compression to express clots; may need manual exploration |
| Secondary PPH (>24h) with retained products | Ultrasound guidance; surgical evacuation; antibiotics |
| Sign | What It Means |
| Blood not clotting in wound/drapes | Clotting factor deficiency |
| Oozing from IV sites, gums, old punctures | Systemic coagulopathy |
| Ecchymoses appearing | Platelet/factor deficiency |
| Bedside clotting test abnormal | DIC or factor deficiency |
| Component | Product | Dose | Target |
|
Red cells
|
PRBC | Transfuse for Hb <7-8 g/dL or ongoing bleeding | Hb >7-8 g/dL |
|
Clotting factors
|
FFP | 15-20 mL/kg (typically 4-6 units) | PT/aPTT <1.5× control |
|
Fibrinogen
|
Cryoprecipitate | 10 units (or 1 pool) | Fibrinogen >2 g/L |
| Fibrinogen concentrate | 2-4 g (if available) | Fibrinogen >2 g/L | |
|
Platelets
|
Platelet concentrate | 1 adult dose (4-6 units or 1 SDP) | Platelets >50,000/μL (>75,000 if ongoing bleeding) |
🚨 Hypothermia, acidosis, and hypocalcemia worsen coagulopathy. Treat aggressively.
| Product | Characteristics |
| Bakri balloon | Purpose-built, drainage channel, can measure ongoing loss |
| Ebb balloon | Dual balloon (uterine + vaginal) |
| BT-Cath | Similar to Bakri |
| Suture | Description |
|
Hayman
|
Simpler; does not require uterine incision; vertical sutures from anterior to posterior |
|
Cho (Square sutures)
|
Multiple square sutures through full thickness; good for focal bleeding |
|
Pereira
|
Combination of transverse and longitudinal sutures |
| Type | Advantages | Disadvantages |
|
Subtotal (Supracervical)
|
Faster, less urological injury, less blood loss | Cervical stump may bleed if placenta praevia/accreta |
|
Total
|
Definitive; no cervical stump issues | Longer, more technically demanding, higher complication risk |
| Procedure | Indication |
|
Uterine artery embolization
|
Atony, accreta (pre-planned), AV malformation, pseudo-aneurysm |
|
Internal iliac artery embolization
|
Broader haemorrhage control |
|
Balloon occlusion (planned)
|
Anticipated accreta; placed before CS |
| Product | Indication | Dose |
|
PRBC
|
Hb <7 g/dL (or <8 g/dL in cardiac disease or ongoing bleeding) | 1 unit raises Hb by ~1 g/dL |
|
FFP
|
PT/INR or aPTT >1.5× normal; empiric in massive transfusion | 15-20 mL/kg |
|
Platelets
|
<50,000/μL with bleeding; <75,000/μL in ongoing haemorrhage | 1 adult dose |
|
Cryoprecipitate
|
Fibrinogen <2 g/L | 10 units |
| Situation | Action |
|
Crossmatch available
|
Crossmatched blood (safest) |
|
No time for crossmatch
|
Type-specific uncrossmatched blood (Group compatible) |
|
Unknown blood group, life-threatening
|
O-negative PRBC (or O-positive if Rh-neg unavailable) |
🚨 Never delay transfusion for crossmatch in life-threatening haemorrhage. O-negative or group-specific blood is acceptable.
| Complication | Signs | Management |
|
Transfusion reaction
|
Fever, chills, rash, dyspnoea, hypotension | Stop transfusion; supportive care; notify blood bank |
|
TACO (overload)
|
Dyspnoea, hypertension, JVP elevated | Slow/stop transfusion; diuretics |
|
TRALI
|
Acute lung injury within 6h; bilateral infiltrates, hypoxia | Supportive; oxygen; may need ventilation |
|
Hypocalcemia
|
Citrate toxicity; prolonged QT, tetany | Calcium gluconate 10 mL 10% IV |
|
Hypothermia
|
Cold products | Use blood warmer |
|
Hyperkalaemia
|
Especially old blood | Monitor potassium; treat if symptomatic |
| Action | Details |
|
Monitoring
|
ICU/HDU level care if severe PPH; q15-30 min vitals initially |
|
Uterine tone
|
Continue to assess; continue oxytocin infusion for minimum 4 hours |
|
Urine output
|
Target ≥0.5 mL/kg/hr; Foley remains in situ |
|
Bleeding
|
Monitor pad/drapes; ongoing bleeding → reassess |
|
Labs
|
Repeat CBC, coagulation at 2-4 hours; ABG if was acidotic |
|
VTE prophylaxis
|
Graduated compression stockings; mechanical prophylaxis while bleeding risk persists |
| Investigation | Purpose |
| Serial CBC | Confirm Hb stable; may continue to drop with fluid shifts |
| Coagulation (PT, aPTT, fibrinogen) | Ensure normalized; guide further blood products |
| RFT | Exclude acute kidney injury |
| LFT | Baseline; especially if HELLP/preeclampsia |
| ABG/Lactate | Ensure clearance of acidosis |
| Echo | If suspected cardiac injury (AFE, massive transfusion) |
| Issue | Management |
|
Anaemia
|
Oral iron supplementation; may need continued transfusion if symptomatic/Hb <7 |
|
Sheehan syndrome
|
Suspect if failure to lactate; test pituitary function (TSH, cortisol, etc.) |
|
Thromboprophylaxis
|
Low molecular weight heparin once haemostasis secured (usually 24-48h post); balance bleeding vs clot risk |
|
Psychological
|
Debrief patient; watch for PTSD; offer counseling |
|
Contraception
|
Discuss timing of future pregnancy; may need interval for recovery |
| Route | Indication | Options |
|
Oral
|
Mild-moderate anaemia, tolerating oral | Ferrous sulfate 200 mg TDS (60 mg elemental iron TDS); take with vitamin C; avoid with tea/antacids |
|
IV
|
Severe anaemia (Hb <8), intolerance to oral, rapid correction needed | Ferric carboxymaltose 1000 mg single dose (or 500 mg × 2); Iron sucrose 200 mg × 5 doses |
| Cause | Frequency |
| Subinvolution of placental site ± infection | Most common |
| Retained products of conception | Common |
| Endometritis | Common |
| Pseudoaneurysm of uterine artery | Rare |
| Gestational trophoblastic disease | Rare |
| Intervention | Details |
|
Cell salvage
|
May be acceptable to some JW (own blood recycled) |
|
Tranexamic acid
|
Give early |
|
IV Iron
|
Pre-operatively if time |
|
Erythropoietin
|
Pre-operatively if time (EPO 40,000 units SC weekly) |
|
Minimize blood loss
|
Meticulous haemostasis, UBT, compression sutures |
|
Tolerate lower Hb
|
May tolerate Hb as low as 5-6 g/dL if normovolemic and not bleeding |
|
Minimize phlebotomy
|
Paediatric tubes; minimize testing |
| Additional Considerations | Details |
| Higher expected blood loss | 1000 mL threshold for “severe” |
| Visible causes | Extensions of incision, broad ligament haematoma, coagulopathy |
| Lower segment atony | May need figure-of-8 sutures at angles |
| Placenta accreta spectrum | Higher risk if previous CS + anterior placenta |
| Rapid access to abdominal cavity | Already open or can re-open quickly |
| Factor | Relative Risk |
| Previous CS + Placenta praevia | Highest risk |
| 1 prior CS + praevia | ~3% accreta |
| 2 prior CS + praevia | ~11% accreta |
| ≥3 prior CS + praevia | ~40% accreta |
| Previous myomectomy | Increased risk |
| Previous curettage | Increased risk |
| Component | Details |
|
Timing
|
Before discharge and at postnatal follow-up |
|
What happened
|
Explain events in understandable terms |
|
Why it happened
|
Cause if known |
|
What was done
|
Interventions, transfusions, surgery |
|
Implications
|
Effect on future fertility/pregnancies |
|
Emotional support
|
Acknowledge trauma; offer counseling if needed |
|
Written summary
|
Provide discharge summary with key details |
|
Follow-up plan
|
When to return, red flags |
| Type | Frequency |
|
PPH simulation
|
Monthly at minimum |
|
MTP activation drill
|
Quarterly |
|
Full team drill with debrief
|
Quarterly |
Medical Advisory
Clinical guidelines are subject to change. Physicians should exercise their regular clinical judgment. This protocol does not replace individual institutional policies. Verified for Q1 2026.
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